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Distinct Modulations of Human Capsaicin Receptor by Protons and Magnesium through Different Domains
The capsaicin receptor (TRPV1) is a nonselective cation channel that integrates multiple painful stimuli, including capsaicin, protons, and heat. Protons facilitate the capsaicin- and heat-induced currents by decreasing thermal threshold or increasing agonist potency for TRPV1 activation (Tominaga,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857033/ https://ncbi.nlm.nih.gov/pubmed/20145248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.058727 |
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