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A highly accurate platform for clone-specific mutation discovery enables the study of active mutational processes
Bulk whole genome sequencing (WGS) enables the analysis of tumor evolution but, because of depth limitations, can only identify old mutational events. The discovery of current mutational processes for predicting the tumor’s evolutionary trajectory requires dense sequencing of individual clones or si...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7228773/ https://ncbi.nlm.nih.gov/pubmed/32255426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55207 |
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