A highly accurate platform for clone-specific mutation discovery enables the study of active mutational processes

Bulk whole genome sequencing (WGS) enables the analysis of tumor evolution but, because of depth limitations, can only identify old mutational events. The discovery of current mutational processes for predicting the tumor’s evolutionary trajectory requires dense sequencing of individual clones or si...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Carrami, Eli M, Sharifzadeh, Sahand, Wietek, Nina C, Artibani, Mara, El-Sahhar, Salma, Sauka-Spengler, Tatjana, Yau, Christopher, Tresp, Volker, Ahmed, Ahmed A
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Cancer Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228773/
https://ncbi.nlm.nih.gov/pubmed/32255426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55207
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