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R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors
During kidney development, WNT/β-catenin signalling has to be tightly controlled to ensure proliferation and differentiation of nephron progenitor cells. Here, we show in mice that the signalling molecules RSPO1 and RSPO3 act in a functionally redundant manner to permit WNT/β-catenin signalling and...
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| 出版年: | eLife |
|---|---|
| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7228766/ https://ncbi.nlm.nih.gov/pubmed/32324134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53895 |
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