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Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4

Coronary artery anomalies are common congenital disorders with serious consequences in adult life. Coronary circulation begins when the coronary stems form connections between the aorta and the developing vascular plexus. We recently identified the WNT signaling modulator R-spondin 3 (Rspo3), as a c...

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Bibliographic Details
Published in:Dev Biol
Main Authors: Da Silva, Fabio, Massa, Filippo, Motamedi, Fariba Jian, Vidal, Valerie, Rocha, Ana Sofia, Gregoire, Elodie P., Cai, Chen-Leng, Wagner, Kay Dietrich, Schedl, Andreas
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365680/
https://ncbi.nlm.nih.gov/pubmed/29859889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2018.05.024
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