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Deletion of inositol polyphosphate 4-phosphatase type-II B affects spermatogenesis in mice
Inositol polyphosphate-4-phosphatase type II (INPP4B) is a dual-specificity phosphatase that acts as a tumor suppressor in multiple cancers. INPP4B dephosphorylates phospholipids at the 4th position of the inositol ring and inhibits AKT and PKC signaling by hydrolyzing of PI(3,4)P2 and PI(4,5)P2, re...
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| Veröffentlicht in: | PLoS One |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7228085/ https://ncbi.nlm.nih.gov/pubmed/32413098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233163 |
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