Deletion of inositol polyphosphate 4-phosphatase type-II B affects spermatogenesis in mice

Inositol polyphosphate-4-phosphatase type II (INPP4B) is a dual-specificity phosphatase that acts as a tumor suppressor in multiple cancers. INPP4B dephosphorylates phospholipids at the 4th position of the inositol ring and inhibits AKT and PKC signaling by hydrolyzing of PI(3,4)P2 and PI(4,5)P2, re...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Ceyhan, Yasemin, Zhang, Manqi, Guo, Jingtao, Sandoval, Carlos G., Vacher, Jean, Kaftanovskaya, Elena M., Agoulnik, Alexander I., Agoulnik, Irina U.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228085/
https://ncbi.nlm.nih.gov/pubmed/32413098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233163
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