Targeted Deletion of Minpp1 Provides New Insight into the Activity of Multiple Inositol Polyphosphate Phosphatase In Vivo

Multiple inositol polyphosphate phosphatase (Minpp1) metabolizes inositol 1,3,4,5,6-pentakisphosphate (InsP(5)) and inositol hexakisphosphate (InsP(6)) with high affinity in vitro. However, Minpp1 is compartmentalized in the endoplasmic reticulum (ER) lumen, where access of enzyme to these predomina...

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Detalhes bibliográficos
Main Authors: Chi, Hongbo, Yang, Xiaonian, Kingsley, Paul D., O'Keefe, Regis J., Puzas, J. Edward, Rosier, Randy N., Shears, Stephen B., Reynolds, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86124/
https://ncbi.nlm.nih.gov/pubmed/10938126
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