Targeted Deletion of Minpp1 Provides New Insight into the Activity of Multiple Inositol Polyphosphate Phosphatase In Vivo

Multiple inositol polyphosphate phosphatase (Minpp1) metabolizes inositol 1,3,4,5,6-pentakisphosphate (InsP(5)) and inositol hexakisphosphate (InsP(6)) with high affinity in vitro. However, Minpp1 is compartmentalized in the endoplasmic reticulum (ER) lumen, where access of enzyme to these predomina...

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Опубликовано в::	Mol Cell Biol
Главные авторы:	Chi, Hongbo, Yang, Xiaonian, Kingsley, Paul D., O'Keefe, Regis J., Puzas, J. Edward, Rosier, Randy N., Shears, Stephen B., Reynolds, Paul R.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 2000
Предметы:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86124/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10938126/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.17.6496-6507.2000
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