SAT-326 INPP4B Suppresses Prostate Inflammation And Protects Mice Fed With High-fat Diet From The Development Of Prostate Intraepithelial Neoplasia

High fat diet leads to obesity, chronic inflammation, accelerated prostate cancer progression, and decreased survival. INPP4B, a dual specificity phosphatase, is a tumor suppressor which opposes Akt and PKC signaling pathways activated in response to obesity and prostate cancer progression. Previous...

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Bibliographic Details
Published in:J Endocr Soc
Main Authors: Zhang, Manqi, Vasquez, Judy, Kaftanovskaya, Elena, Agoulnik, Alexander, Vacher, Jean, Ittmann, Michael, Agoulnik, Irina
Format: Artigo
Language:Inglês
Published: Endocrine Society 2019
Subjects:
Tumor Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552162/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-326
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