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BRD4 Inhibition Protects Against Acute Pancreatitis Through Restoring Impaired Autophagic Flux

Impaired autophagy has been shown to play a critical role in experimental and human acute pancreatitis (AP). However, the mechanism for transcriptional regulation of autophagy remains largely unknown. In this study, we aim to explore the role of BRD4 (bromodomain-containing protein 4), a transcripti...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Shen, Shuangjun, Li, Bin, Dai, Juanjuan, Wu, Zengkai, He, Yan, Wen, Li, Wang, Xingpeng, Hu, Guoyong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227015/
https://ncbi.nlm.nih.gov/pubmed/32457617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00618
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