Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration

Oxidative stress-induced mitochondrial dysfunction and nucleus pulposus (NP) cell apoptosis play crucial roles in the development of intervertebral disc degeneration (IDD). Increasing studies have shown that interventions targeting impaired autophagic flux can maintain cellular homeostasis by reliev...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Kang, Liang, Xiang, Qian, Zhan, Shengfeng, Song, Yu, Wang, Kun, Zhao, Kangcheng, Li, Shuai, Shao, Zengwu, Yang, Cao, Zhang, Yukun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954474/
https://ncbi.nlm.nih.gov/pubmed/31976028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7810320
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