Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration

Oxidative stress-induced mitochondrial dysfunction and nucleus pulposus (NP) cell apoptosis play crucial roles in the development of intervertebral disc degeneration (IDD). Increasing studies have shown that interventions targeting impaired autophagic flux can maintain cellular homeostasis by reliev...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oxid Med Cell Longev
Egile Nagusiak: Kang, Liang, Xiang, Qian, Zhan, Shengfeng, Song, Yu, Wang, Kun, Zhao, Kangcheng, Li, Shuai, Shao, Zengwu, Yang, Cao, Zhang, Yukun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954474/
https://ncbi.nlm.nih.gov/pubmed/31976028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7810320
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