BRD4 Inhibition Protects Against Acute Pancreatitis Through Restoring Impaired Autophagic Flux

Impaired autophagy has been shown to play a critical role in experimental and human acute pancreatitis (AP). However, the mechanism for transcriptional regulation of autophagy remains largely unknown. In this study, we aim to explore the role of BRD4 (bromodomain-containing protein 4), a transcripti...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Shen, Shuangjun, Li, Bin, Dai, Juanjuan, Wu, Zengkai, He, Yan, Wen, Li, Wang, Xingpeng, Hu, Guoyong
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227015/
https://ncbi.nlm.nih.gov/pubmed/32457617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00618
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