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Direct regulation of Chk1 protein stability by E3 ubiquitin ligase HUWE1.
The HECT E3 ubiquitin ligase HUWE1 is required for a wide array of important functions in cell biology. Although HUWE1 is known to play a role in DNA damage signaling, the mechanism(s) that underlies this function remains elusive. HUWE1 regulates effectors of DNA replication and genotoxic stress tol...
Shranjeno v:
| izdano v: | FEBS J |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7226928/ https://ncbi.nlm.nih.gov/pubmed/31713291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.15132 |
| Oznake: |
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