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Regulation of the p53 Family Proteins by the Ubiquitin Proteasomal Pathway

The tumor suppressor p53 and its homologues, p63 and p73, play a pivotal role in the regulation of the DNA damage response, cellular homeostasis, development, aging, and metabolism. A number of mouse studies have shown that a genetic defect in the p53 family could lead to spontaneous tumor developme...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bang, Scott, Kaur, Sandeep, Kurokawa, Manabu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981958/
https://ncbi.nlm.nih.gov/pubmed/31905981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010261
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