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Cdc6 Stability Is Regulated by the Huwe1 Ubiquitin Ligase after DNA Damage
The Cdc6 protein is an essential component of pre-replication complexes (preRCs), which assemble at origins of DNA replication during the G1 phase of the cell cycle. Previous studies have demonstrated that, in response to ionizing radiation, Cdc6 is ubiquitinated by the anaphase promoting complex (A...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1951745/ https://ncbi.nlm.nih.gov/pubmed/17567951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-02-0173 |
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