Human Alphoid(tetO) Artificial Chromosome as a Gene Therapy Vector for the Developing Hemophilia A Model in Mice

Human artificial chromosomes (HACs), including the de novo synthesized alphoid(tetO)-HAC, are a powerful tool for introducing genes of interest into eukaryotic cells. HACs are mitotically stable, non-integrative episomal units that have a large transgene insertion capacity and allow efficient and st...

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Xehetasun bibliografikoak
Argitaratua izan da:Cells
Egile Nagusiak: Ponomartsev, Sergey V., Sinenko, Sergey A., Skvortsova, Elena V., Liskovykh, Mikhail A., Voropaev, Ivan N., Savina, Maria M., Kuzmin, Andrey A., Kuzmina, Elena Yu., Kondrashkina, Alexandra M., Larionov, Vladimir, Kouprina, Natalay, Tomilin, Alexey N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226776/
https://ncbi.nlm.nih.gov/pubmed/32260189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040879
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