Utilizing Genome-Wide mRNA Profiling to Identify the Cytotoxic Chemotherapeutic Mechanism of Triazoloacridone C-1305 as Direct Microtubule Stabilization

Rational drug design and in vitro pharmacology profiling constitute the gold standard in drug development pipelines. Problems arise, however, because this process is often difficult due to limited information regarding the complete identification of a molecule’s biological activities. The increasing...

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Publicat a:Cancers (Basel)
Autors principals: Króliczewski, Jarosław, Bartoszewska, Sylwia, Dudkowska, Magdalena, Janiszewska, Dorota, Biernatowska, Agnieszka, Crossman, David K., Krzymiński, Karol, Wysocka, Małgorzata, Romanowska, Anna, Baginski, Maciej, Markuszewski, Michal, Ochocka, Renata J., Collawn, James F., Sikorski, Aleksander F., Sikora, Ewa, Bartoszewski, Rafal
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226417/
https://ncbi.nlm.nih.gov/pubmed/32252403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040864
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