Utilizing Genome-Wide mRNA Profiling to Identify the Cytotoxic Chemotherapeutic Mechanism of Triazoloacridone C-1305 as Direct Microtubule Stabilization

Rational drug design and in vitro pharmacology profiling constitute the gold standard in drug development pipelines. Problems arise, however, because this process is often difficult due to limited information regarding the complete identification of a molecule’s biological activities. The increasing...

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Publicado no:Cancers (Basel)
Main Authors: Króliczewski, Jarosław, Bartoszewska, Sylwia, Dudkowska, Magdalena, Janiszewska, Dorota, Biernatowska, Agnieszka, Crossman, David K., Krzymiński, Karol, Wysocka, Małgorzata, Romanowska, Anna, Baginski, Maciej, Markuszewski, Michal, Ochocka, Renata J., Collawn, James F., Sikorski, Aleksander F., Sikora, Ewa, Bartoszewski, Rafal
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226417/
https://ncbi.nlm.nih.gov/pubmed/32252403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040864
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