External Beam Radiation Therapy and Enadenotucirev: Inhibition of the DDR and Mechanisms of Radiation-Mediated Virus Increase

Ionising radiation causes cell death through the induction of DNA damage, particularly double-stranded DNA (dsDNA) breaks. Evidence suggests that adenoviruses inhibit proteins involved in the DNA damage response (DDR) to prevent recognition of double-stranded viral DNA genomes as cellular dsDNA brea...

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Bibliografiska uppgifter
I publikationen:Cancers (Basel)
Huvudupphovsmän: Pokrovska, Tzveta D., Jacobus, Egon J., Puliyadi, Rathi, Prevo, Remko, Frost, Sally, Dyer, Arthur, Baugh, Richard, Rodriguez-Berriguete, Gonzalo, Fisher, Kerry, Granata, Giovanna, Herbert, Katharine, Taverner, William K., Champion, Brian R., Higgins, Geoff S., Seymour, Len W., Lei-Rossmann, Janet
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226394/
https://ncbi.nlm.nih.gov/pubmed/32224979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040798
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