Calcium Influx Caused by ER Stress Inducers Enhances Oncolytic Adenovirus Enadenotucirev Replication and Killing through PKCα Activation

Oncolytic viruses represent an emerging approach to cancer therapy. However, better understanding of their interaction with the host cancer cell and approaches to enhance their efficacy are needed. Here, we investigate the effect of chemically induced endoplasmic reticulum (ER) stress on the activit...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Taverner, William K., Jacobus, Egon J., Christianson, John, Champion, Brian, Paton, Adrienne W., Paton, James C., Su, Weiheng, Cawood, Ryan, Seymour, Len W., Lei-Rossmann, Janet
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6931121/
https://ncbi.nlm.nih.gov/pubmed/31890865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2019.09.003
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