Calcium Influx Caused by ER Stress Inducers Enhances Oncolytic Adenovirus Enadenotucirev Replication and Killing through PKCα Activation

Oncolytic viruses represent an emerging approach to cancer therapy. However, better understanding of their interaction with the host cancer cell and approaches to enhance their efficacy are needed. Here, we investigate the effect of chemically induced endoplasmic reticulum (ER) stress on the activit...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Ther Oncolytics
Prif Awduron: Taverner, William K., Jacobus, Egon J., Christianson, John, Champion, Brian, Paton, Adrienne W., Paton, James C., Su, Weiheng, Cawood, Ryan, Seymour, Len W., Lei-Rossmann, Janet
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Gene & Cell Therapy 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6931121/
https://ncbi.nlm.nih.gov/pubmed/31890865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2019.09.003
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