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Strained Conformations of Nucleosides in Active Sites of Nucleoside Phosphorylases
Nucleoside phosphorylases catalyze the reversible phosphorolysis of nucleosides to heterocyclic bases, giving α-d-ribose-1-phosphate or α-d-2-deoxyribose-1-phosphate. These enzymes are involved in salvage pathways of nucleoside biosynthesis. The level of these enzymes is often elevated in tumors, wh...
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| Udgivet i: | Biomolecules |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7226091/ https://ncbi.nlm.nih.gov/pubmed/32260512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10040552 |
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