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Strained Conformations of Nucleosides in Active Sites of Nucleoside Phosphorylases

Nucleoside phosphorylases catalyze the reversible phosphorolysis of nucleosides to heterocyclic bases, giving α-d-ribose-1-phosphate or α-d-2-deoxyribose-1-phosphate. These enzymes are involved in salvage pathways of nucleoside biosynthesis. The level of these enzymes is often elevated in tumors, wh...

詳細記述

保存先:
書誌詳細
出版年:Biomolecules
主要な著者: Il’icheva, Irina A., Polyakov, Konstantin M., Mikhailov, Sergey N.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226091/
https://ncbi.nlm.nih.gov/pubmed/32260512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10040552
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