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STAT5 is Expressed in CD34(+)/CD38(−) Stem Cells and Serves as a Potential Molecular Target in Ph-Negative Myeloproliferative Neoplasms

Janus kinase 2 (JAK2) and signal transducer and activator of transcription-5 (STAT5) play a key role in the pathogenesis of myeloproliferative neoplasms (MPN). In most patients, JAK2 V617F or CALR mutations are found and lead to activation of various downstream signaling cascades and molecules, incl...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cancers (Basel)
Κύριοι συγγραφείς: Hadzijusufovic, Emir, Keller, Alexandra, Berger, Daniela, Greiner, Georg, Wingelhofer, Bettina, Witzeneder, Nadine, Ivanov, Daniel, Pecnard, Emmanuel, Nivarthi, Harini, Schur, Florian K. M., Filik, Yüksel, Kornauth, Christoph, Neubauer, Heidi A., Müllauer, Leonhard, Tin, Gary, Park, Jisung, de Araujo, Elvin D., Gunning, Patrick T., Hoermann, Gregor, Gouilleux, Fabrice, Kralovics, Robert, Moriggl, Richard, Valent, Peter
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: MDPI 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225958/
https://ncbi.nlm.nih.gov/pubmed/32326377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12041021
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