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IL-4 downregulates expression of the target receptor CD30 in neoplastic canine mast cells
CD30 is a novel therapeutic target in human mast cell (MC) neoplasms. In this ‘comparative oncology’ study, we examined CD30 expression and regulation in neoplastic canine MC using a panel of immunomodulatory cytokines [interleukin-2 (IL-2), IL-4, IL-5, IL-6, IL-13 and stem cell factor (SCF)] and th...
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| Veröffentlicht in: | Vet Comp Oncol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5798577/ https://ncbi.nlm.nih.gov/pubmed/27507155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vco.12260 |
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