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IL-4 downregulates expression of the target receptor CD30 in neoplastic canine mast cells

CD30 is a novel therapeutic target in human mast cell (MC) neoplasms. In this ‘comparative oncology’ study, we examined CD30 expression and regulation in neoplastic canine MC using a panel of immunomodulatory cytokines [interleukin-2 (IL-2), IL-4, IL-5, IL-6, IL-13 and stem cell factor (SCF)] and th...

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Publicat a:Vet Comp Oncol
Autors principals: Bauer, K., Hadzijusufovic, E., Cerny-Reiterer, S., Hoermann, G., Reifinger, M., Pirker, A., Valent, P., Willmann, M.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798577/
https://ncbi.nlm.nih.gov/pubmed/27507155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vco.12260
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