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Effects of ibrutinib on proliferation and histamine release in canine neoplastic mast cells

The Bruton's tyrosine kinase (BTK) inhibitor ibrutinib is effective in the treatment of human chronic lymphocytic leukaemia and mantle cell lymphoma. Recent data have shown that ibrutinib also blocks IgE‐dependent activation and histamine release in human basophils (BAs) and mast cells (MCs). T...

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Detalhes bibliográficos
Publicado no:Vet Comp Oncol
Main Authors: Gamperl, Susanne, Stefanzl, Gabriele, Peter, Barbara, Smiljkovic, Dubravka, Bauer, Karin, Willmann, Michael, Valent, Peter, Hadzijusufovic, Emir
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900099/
https://ncbi.nlm.nih.gov/pubmed/31286638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vco.12520
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