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Creating New β-Globin-Expressing Lentiviral Vectors by High-Resolution Mapping of Locus Control Region Enhancer Sequences
Hematopoietic stem cell gene therapy is a promising approach for treating disorders of the hematopoietic system. Identifying combinations of cis-regulatory elements that do not impede packaging or transduction efficiency when included in lentiviral vectors has proven challenging. In this study, we d...
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| I publikationen: | Mol Ther Methods Clin Dev |
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| Huvudupphovsmän: | , , , , , , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society of Gene & Cell Therapy
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7225380/ https://ncbi.nlm.nih.gov/pubmed/32426415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.04.006 |
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