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Berberine Improves Glucose and Lipid Metabolism in HepG2 Cells Through AMPKα1 Activation
AIM: This study is designed to investigate whether or not AMP-activated protein kinase α1 (AMPKα1) is required for natural product berberine (BBR) to improve glucose and lipid metabolism in HepG2 cells. METHODS: AMPKα1 knocked-out (KO, AMPKα1(-/-)) cells were obtained by co-transfection of the CRISP...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7225256/ https://ncbi.nlm.nih.gov/pubmed/32457629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00647 |
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