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Luteolin attenuates doxorubicin-induced cardiotoxicity by modulating the PHLPP1/AKT/Bcl-2 signalling pathway

BACKGROUND: Luteolin (LUT) is a flavonoid found in vegetables and fruits that has diverse functions. Doxorubicin (DOX) is an anthracycline antibiotic that is frequently used for the treatment of various cancers. Unfortunately, the clinical efficacy of DOX is limited by its dose-related cardiotoxicit...

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Publicat a:PeerJ
Autors principals: Zhang, YanDong, Ma, ChengYuan, Liu, ChunShui, Wei, Feng
Format: Artigo
Idioma:Inglês
Publicat: PeerJ Inc. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224230/
https://ncbi.nlm.nih.gov/pubmed/32435528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.8845
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