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Quercetin attenuates doxorubicin cardiotoxicity by modulating Bmi-1 expression

BACKGROUND AND PURPOSE: Doxorubicin-based chemotherapy induces cardiotoxicity, which limits its clinical application. We previously reported the protective effects of quercetin against doxorubicin-induced hepatotoxicity. In this study, we tested the effects of quercetin on the expression of Bmi-1, a...

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Autores principales: Dong, Qinghua, Chen, Long, Lu, Qunwei, Sharma, Sherven, Li, Lei, Morimoto, Sachio, Wang, Guanyu
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209150/
https://ncbi.nlm.nih.gov/pubmed/24902966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12795
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