Computer-Driven Development of an in Silico Tool for Finding Selective Histone Deacetylase 1 Inhibitors

Histone deacetylases (HDACs) are a class of epigenetic modulators overexpressed in numerous types of cancers. Consequently, HDAC inhibitors (HDACIs) have emerged as promising antineoplastic agents. Unfortunately, the most developed HDACIs suffer from poor selectivity towards a specific isoform, limi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Molecules
Hlavní autoři: Sirous, Hajar, Campiani, Giuseppe, Brogi, Simone, Calderone, Vincenzo, Chemi, Giulia
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221830/
https://ncbi.nlm.nih.gov/pubmed/32331470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25081952
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky