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Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation

TATA-box binding protein (TBP) is required for every single transcription event in archaea and eukaryotes. It binds DNA and harbors two repeats with an internal structural symmetry that show sequence asymmetry. At various times in evolution, TBP has acquired multiple interaction partners and differe...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Ravarani, Charles N. J., Flock, Tilman, Chavali, Sreenivas, Anandapadamanaban, Madhanagopal, Babu, M. Madan, Balaji, Santhanam
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221094/
https://ncbi.nlm.nih.gov/pubmed/32404905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16182-z
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