High-resolution structure of TBP with TAF1 reveals anchoring patterns in transcriptional regulation

The general transcription factor TFIID provides a regulatory platform for transcription initiation. Here we present the crystal structure (1.97 Å) and NMR analysis of yeast TAF1 N-terminal domains TAND1 and TAND2 when bound to yeast TBP, together with mutational data. The yTAF1-TAND1, which in itsel...

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Publicado no:Nat Struct Mol Biol
Main Authors: Anandapadamanaban, Madhanagopal, Andresen, Cecilia, Helander, Sara, Ohyama, Yoshifumi, Siponen, Marina I., Lundström, Patrik, Kokubo, Tetsuro, Ikura, Mitsuhiko, Moche, Martin, Sunnerhagen, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972576/
https://ncbi.nlm.nih.gov/pubmed/23851461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2611
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