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TMEM16A drives renal cyst growth by augmenting Ca(2+) signaling in M1 cells
ABSTRACT: Polycystic kidney disease (PKD) leads to continuous decline of renal function by growth of renal cysts. Enhanced proliferation and transepithelial chloride secretion through cystic fibrosis transmembrane conductance regulator (CFTR) and Ca(2+)-activated TMEM16A Cl(−) channels is thought to...
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| Publicado no: | J Mol Med (Berl) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7220898/ https://ncbi.nlm.nih.gov/pubmed/32185407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01894-y |
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