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Mitigating off-target effects in CRISPR/Cas9-mediated in vivo gene editing

The rapid advancement of genome editing technologies has opened up new possibilities in the field of medicine. Nuclease-based techniques such as the CRISPR/Cas9 system are now used to target genetically linked disorders that were previously hard-to-treat. The CRISPR/Cas9 gene editing approach wields...

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Detalhes bibliográficos
Publicado no:J Mol Med (Berl)
Main Authors: Han, Hua Alexander, Pang, Jeremy Kah Sheng, Soh, Boon-Seng
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7220873/
https://ncbi.nlm.nih.gov/pubmed/32198625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01893-z
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