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Off-target predictions in CRISPR-Cas9 gene editing using deep learning
MOTIVATION: The prediction of off-target mutations in CRISPR-Cas9 is a hot topic due to its relevance to gene editing research. Existing prediction methods have been developed; however, most of them just calculated scores based on mismatches to the guide sequence in CRISPR-Cas9. Therefore, the exist...
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| Udgivet i: | Bioinformatics |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6129261/ https://ncbi.nlm.nih.gov/pubmed/30423072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty554 |
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