טוען...
Generation of novel Il2rg-knockout mice with clustered regularly interspaced short palindromic repeats (CRISPR) and Cas9
X-linked severe combined immunodeficiency (X-SCID) is an inherited genetic disorder. A majority of X-SCID subjects carries point mutations in the Interleukin-2 receptor gamma chain (IL2RG) gene. In contrast, Il2rg-knockout mice recapitulating X-SCID phenotype lack a large part of Il2rg instead of po...
שמור ב:
| הוצא לאור ב: | Exp Anim |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Japanese Association for Laboratory Animal Science
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7220705/ https://ncbi.nlm.nih.gov/pubmed/31801915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.19-0120 |
| תגים: |
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