Nalaganje...
Hairless-knockout piglets generated using the clustered regularly interspaced short palindromic repeat/CRISPR-associated-9 exhibit abnormalities in the skin and thymus
The nuclear receptor corepressor Hairless (HR) interacts with nuclear receptors and controls expression of specific target genes involved in hair morphogenesis and hair follicle cycling. Patients with HR gene mutations exhibit atrichia, and in rare cases, immunodeficiency. Pigs with HR gene mutation...
Shranjeno v:
| izdano v: | Exp Anim |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Japanese Association for Laboratory Animal Science
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6842791/ https://ncbi.nlm.nih.gov/pubmed/31308290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.19-0018 |
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