Novel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing

Copy number alterations (CNAs) play an important role in molding the genomes of breast cancers and have been shown to be clinically useful for prognostic and therapeutic purposes. However, our knowledge of intra-tumoral genetic heterogeneity of this important class of somatic alterations is limited....

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Baslan, Timour, Kendall, Jude, Volyanskyy, Konstantin, McNamara, Katherine, Cox, Hilary, D'Italia, Sean, Ambrosio, Frank, Riggs, Michael, Rodgers, Linda, Leotta, Anthony, Song, Junyan, Mao, Yong, Wu, Jie, Shah, Ronak, Gularte-Mérida, Rodrigo, Chadalavada, Kalyani, Nanjangud, Gouri, Varadan, Vinay, Gordon, Assaf, Curtis, Christina, Krasnitz, Alex, Dimitrova, Nevenka, Harris, Lyndsay, Wigler, Michael, Hicks, James
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7220379/
https://ncbi.nlm.nih.gov/pubmed/32401198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51480
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