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Adding combination immunotherapy consisting of cancer vaccine, anti-PD-1 and anti-CSF1R antibodies to gemcitabine improves anti-tumor efficacy in murine model of pancreatic ductal adenocarcinoma

BACKGROUND: Immunotherapy can take advantage of the immunogenic response that chemotherapy elicits in tumors. Gemcitabine is a standard agent used in the treatment of pancreatic cancer, with known effects on the tumor immune microenvironment. The combination immunotherapy of the GVAX cancer vaccine,...

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Publicado en:Ann Pancreat Cancer
Main Authors: Saung, May Tun, Zheng, Lei
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7220030/
https://ncbi.nlm.nih.gov/pubmed/32405624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/apc.2019.11.01
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