Comparing the intra-tumoral distribution of Gemcitabine, 5-Fluorouracil, and Capecitabine in a murine model of pancreatic ductal adenocarcinoma

PURPOSE: To develop a technique to compare the intra-tumoral distribution of the drug gemcitabine, its surrogate [(18)F]-fluoroarabinocytosine ([(18)F]-FAC) and related chemotherapeutics 5-FU and capecitabine in a pre-clinical model of pancreatic ductal adenocarcinoma (PDAC). EXPERIMENTAL DESIGN: Us...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fanchon, Louise M., Russell, James, Pillarsetty, Nagavarakishore, O’Donoghue, Isabella, Gangangari, Kishore, Yu, Kenneth H., Humm, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162455/
https://ncbi.nlm.nih.gov/pubmed/32298392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231745
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