Modulating the Tumor Microenvironment via Oncolytic Viruses and CSF-1R Inhibition Synergistically Enhances Anti-PD-1 Immunotherapy

Immunotherapy based on the immune checkpoint blockade has emerged as the most promising approach for cancer therapy. However, the proportion of colorectal cancer patients who benefit from immunotherapy is small due to the immunosuppressive tumor microenvironment. Hence, combination immunotherapy is...

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Gepubliceerd in:Mol Ther
Hoofdauteurs: Shi, Gang, Yang, Qianmei, Zhang, Yujing, Jiang, Qingyuan, Lin, Yi, Yang, Shenshen, Wang, Huiling, Cheng, Lin, Zhang, Xin, Li, Yimin, Wang, Qingnan, Liu, Yi, Wang, Qin, Zhang, Hantao, Su, Xiaolan, Dai, Lei, Liu, Lei, Zhang, Shuang, Li, Jia, Li, Zhi, Yang, Yang, Yu, Dechao, Wei, Yuquan, Deng, Hongxin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2019
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319306/
https://ncbi.nlm.nih.gov/pubmed/30527756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.11.010
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