Modulating the Tumor Microenvironment via Oncolytic Viruses and CSF-1R Inhibition Synergistically Enhances Anti-PD-1 Immunotherapy

Immunotherapy based on the immune checkpoint blockade has emerged as the most promising approach for cancer therapy. However, the proportion of colorectal cancer patients who benefit from immunotherapy is small due to the immunosuppressive tumor microenvironment. Hence, combination immunotherapy is...

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Bibliografiset tiedot
Julkaisussa:Mol Ther
Päätekijät: Shi, Gang, Yang, Qianmei, Zhang, Yujing, Jiang, Qingyuan, Lin, Yi, Yang, Shenshen, Wang, Huiling, Cheng, Lin, Zhang, Xin, Li, Yimin, Wang, Qingnan, Liu, Yi, Wang, Qin, Zhang, Hantao, Su, Xiaolan, Dai, Lei, Liu, Lei, Zhang, Shuang, Li, Jia, Li, Zhi, Yang, Yang, Yu, Dechao, Wei, Yuquan, Deng, Hongxin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Gene & Cell Therapy 2019
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319306/
https://ncbi.nlm.nih.gov/pubmed/30527756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.11.010
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