Modulating the Tumor Microenvironment via Oncolytic Viruses and CSF-1R Inhibition Synergistically Enhances Anti-PD-1 Immunotherapy

Immunotherapy based on the immune checkpoint blockade has emerged as the most promising approach for cancer therapy. However, the proportion of colorectal cancer patients who benefit from immunotherapy is small due to the immunosuppressive tumor microenvironment. Hence, combination immunotherapy is...

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Podrobná bibliografie
Vydáno v:Mol Ther
Hlavní autoři: Shi, Gang, Yang, Qianmei, Zhang, Yujing, Jiang, Qingyuan, Lin, Yi, Yang, Shenshen, Wang, Huiling, Cheng, Lin, Zhang, Xin, Li, Yimin, Wang, Qingnan, Liu, Yi, Wang, Qin, Zhang, Hantao, Su, Xiaolan, Dai, Lei, Liu, Lei, Zhang, Shuang, Li, Jia, Li, Zhi, Yang, Yang, Yu, Dechao, Wei, Yuquan, Deng, Hongxin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2019
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319306/
https://ncbi.nlm.nih.gov/pubmed/30527756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.11.010
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