Modulating the Tumor Microenvironment via Oncolytic Viruses and CSF-1R Inhibition Synergistically Enhances Anti-PD-1 Immunotherapy

Immunotherapy based on the immune checkpoint blockade has emerged as the most promising approach for cancer therapy. However, the proportion of colorectal cancer patients who benefit from immunotherapy is small due to the immunosuppressive tumor microenvironment. Hence, combination immunotherapy is...

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Dades bibliogràfiques
Publicat a:Mol Ther
Autors principals: Shi, Gang, Yang, Qianmei, Zhang, Yujing, Jiang, Qingyuan, Lin, Yi, Yang, Shenshen, Wang, Huiling, Cheng, Lin, Zhang, Xin, Li, Yimin, Wang, Qingnan, Liu, Yi, Wang, Qin, Zhang, Hantao, Su, Xiaolan, Dai, Lei, Liu, Lei, Zhang, Shuang, Li, Jia, Li, Zhi, Yang, Yang, Yu, Dechao, Wei, Yuquan, Deng, Hongxin
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2019
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319306/
https://ncbi.nlm.nih.gov/pubmed/30527756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.11.010
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