Modulating the Tumor Microenvironment via Oncolytic Viruses and CSF-1R Inhibition Synergistically Enhances Anti-PD-1 Immunotherapy

Immunotherapy based on the immune checkpoint blockade has emerged as the most promising approach for cancer therapy. However, the proportion of colorectal cancer patients who benefit from immunotherapy is small due to the immunosuppressive tumor microenvironment. Hence, combination immunotherapy is...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Shi, Gang, Yang, Qianmei, Zhang, Yujing, Jiang, Qingyuan, Lin, Yi, Yang, Shenshen, Wang, Huiling, Cheng, Lin, Zhang, Xin, Li, Yimin, Wang, Qingnan, Liu, Yi, Wang, Qin, Zhang, Hantao, Su, Xiaolan, Dai, Lei, Liu, Lei, Zhang, Shuang, Li, Jia, Li, Zhi, Yang, Yang, Yu, Dechao, Wei, Yuquan, Deng, Hongxin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319306/
https://ncbi.nlm.nih.gov/pubmed/30527756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.11.010
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