Cancer Cells Resist Mechanical Destruction in Circulation via RhoA/Actomyosin-Dependent Mechano-Adaptation

During metastasis, cancer cells are exposed to potentially destructive hemodynamic forces including fluid shear stress (FSS) while en route to distant sites. However, prior work indicates that cancer cells are more resistant to brief pulses of high-level FSS in vitro relative to non-transformed epit...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Moose, Devon L., Krog, Benjamin L., Kim, Tae-Hyung, Zhao, Lei, Williams-Perez, Sophia, Burke, Gretchen, Rhodes, Lillian, Vanneste, Marion, Breheny, Patrick, Milhem, Mohammed, Stipp, Christopher S., Rowat, Amy C., Henry, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219793/
https://ncbi.nlm.nih.gov/pubmed/32187555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.02.080
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