ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase

Activating transcription factor 4 (ATF4) is a master transcriptional regulator of the integrated stress response (ISR) that enables cell survival under nutrient stress. The mechanisms by which ATF4 couples metabolic stresses to specific transcriptional outputs remain unknown. Using functional genomi...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Williams, Robert T., Guarecuco, Rohiverth, Gates, Leah A., Barrows, Douglas, Passarelli, Maria C., Carey, Bryce, Baudrier, Lou, Jeewajee, Swarna, La, Konnor, Prizer, Benjamin, Malik, Sohail, Garcia-Bermudez, Javier, Zhu, Xiphias Ge, Cantor, Jason, Molina, Henrik, Carroll, Thomas, Roeder, Robert G., Abdel-Wahab, Omar, Allis, C. David, Birsoy, Kıvanç
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219601/
https://ncbi.nlm.nih.gov/pubmed/32268116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.03.008
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