Inhibition of K(Ca)2 and K(v)11.1 Channels in Pigs With Left Ventricular Dysfunction

BACKGROUND: Inhibition of K(Ca)2 channels, conducting I(KCa), can convert atrial fibrillation (AF) to sinus rhythm and protect against its induction. I(KCa) inhibition has been shown to possess functional atrial selectivity with minor effects on ventricles. Under pathophysiological conditions with v...

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Vydáno v:Front Pharmacol
Hlavní autoři: Citerni, Carlotta, Kirchhoff, Jeppe, Olsen, Lisbeth Høier, Sattler, Stefan Michael, Grunnet, Morten, Edvardsson, Nils, Bentzen, Bo Hjorth, Diness, Jonas Goldin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219273/
https://ncbi.nlm.nih.gov/pubmed/32435191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00556
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